Pyrah, Ian: search on Z-Library

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1

Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody

Boyce, Rogely Waite, Brown, Danielle, Felx, Melanie, Mellal, Nacera, Locher, Kathrin, Pyrah, Ian, Ominsky, Michael S., Taylor, Scott

Journal:

Year:

2018

Language:

english

File:

PDF, 338 KB

english, 2018

2

Rate Effects in Pressuremeter Tests in Clays

Anderson, William F., Pyrah, Ian C., Ali, Faisal Haji

Journal:

Journal of Geotechnical Engineering

Year:

1987

Language:

english

File:

PDF, 830 KB

english, 1987

3

Thermal degradation and flame retardance in copolymers of methyl methacrylate with diethyl(methacryloyloxymethyl)phosphonate

John R Ebdon, Barry J Hunt, Paul Joseph, Christopher S Konkel, Dennis Price, Kelly Pyrah, T.Richard Hull, G.John Milnes, Stephen B Hill, Christopher I Lindsay, John McCluskey, Ian Robinson

Journal:

Polymer Degradation and Stability

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

4

Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody

Paul J. Kostenuik, Susan Y. Smith, Jacquelin Jolette, Joseph Schroeder, Ian Pyrah, Michael S. Ominsky

Journal:

Year:

2011

Language:

english

File:

PDF, 1010 KB

english, 2011

5

A Particle Tracking Model for Non-Fickian Subsurface Diffusion

Paul S. Addison, Bo Qu, Alberto S. Ndumu, Ian C. Pyrah

Journal:

Mathematical Geosciences

Year:

1998

Language:

english

File:

PDF, 1.56 MB

english, 1998

6

Global recognition of qualified toxicologic pathologists: Credential review as a potential route for recognizing the proficiency of pathologists involved in regulatory-type nonclinical studies

Robert A. Ettlin, Brad Bolon, Ian Pyrah, Yoichi Konishi, Hugh E. Black

Journal:

Experimental and Toxicologic Pathology

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

7

Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats

Taylor, Scott, Hu, Rong, Pacheco, Efrain, Locher, Kathrin, Pyrah, Ian, Ominsky, Michael S., Boyce, Rogely Waite

Journal:

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

8

Nonclinical investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration throughout pregnancy

Moffat, Graeme J., Davies, Rhian, Kwon, Gayle, Retter, Marc W., Kanapuram, Sekhar, Moore, Meghan, Loomis, Mark, Chellman, Gary J., Pyrah, Ian T.G.

Journal:

Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

9

Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys

Michael S. Ominsky, Brian Stouch, Joseph Schroeder, Ian Pyrah, Marina Stolina, Susan Y. Smith, Paul J. Kostenuik

Journal:

Year:

2011

Language:

english

File:

PDF, 773 KB

english, 2011

10

Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy

Moffat, Graeme J., Davies, Rhian, Kwon, Gayle, Retter, Marc W., Chellman, Gary J., Kanapuram, Sekhar, Moore, Meghan, Loomis, Mark, Wang, Wei, Pyrah, Ian T.G.

Journal:

Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 693 KB

english, 2014

11

Expression of the Immediate-Early Genes, c- fos , c- jun , and c- myc : A Comparison in Rats of Nongenotoxic Hepatocarcinogens with Noncarcinogenic Liver Mitogens

Hasmall, Susan C., Pyrah, Ian T. G., Soames, Anthony R., Roberts, Ruth A.

Journal:

Toxicological Sciences

Year:

1997

Language:

english

File:

PDF, 3.91 MB

english, 1997

12

Review of the Application of RNA Interference Technology in the Pharmaceutical Industry

Martineau, Henny, Pyrah, Ian

Journal:

Toxicologic Pathology

Year:

2007

Language:

english

File:

PDF, 5.73 MB

english, 2007

13

Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys

Ominsky, Michael S, Boyd, Steven K, Varela, Aurore, Jolette, Jacquelin, Felx, Melanie, Doyle, Nancy, Mellal, Nacera, Smith, Susan Y, Locher, Kathrin, Buntich, Sabina, Pyrah, Ian, Boyce, Rogely W

Journal:

Journal of Bone and Mineral Research

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

14

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats

Taylor, Scott, Ominsky, Michael S., Hu, Rong, Pacheco, Efrain, He, Yudong D., Brown, Danielle L., Aguirre, J. Ignacio, Wronski, Thomas J., Buntich, Sabina, Afshari, Cynthia A., Pyrah, Ian, Nioi, Paul,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

15

Global recognition of qualified toxicologic pathologists: Where we are now and where we need to go

Robert A. Ettlin, Brad Bolon, Ian Pyrah, Yoichi Konishi, Hugh E. Black

Journal:

Experimental and Toxicologic Pathology

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

16

Reproductive toxicity of denosumab in cynomolgus monkeys

Bussiere, Jeanine L., Pyrah, Ian, Boyce, Rogely, Branstetter, Dan, Loomis, Mark, Andrews-Cleavenger, Dina, Farman, Cynthia, Elliott, Glenn, Chellman, Gary

Journal:

Reproductive Toxicology

Year:

2013

Language:

english

File:

PDF, 4.25 MB

english, 2013

17

Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats

Nioi, Paul, Taylor, Scott, Hu, Rong, Pacheco, Efrain, He, Yudong D, Hamadeh, Hisham, Paszty, Chris, Pyrah, Ian, Ominsky, Michael S, Boyce, Rogely Waite

Journal:

Journal of Bone and Mineral Research

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

18

Carcinogenicity risk assessment of romosozumab: A review of scientific weight-of-evidence and findings in a rat lifetime pharmacology study

Chouinard, Luc, Felx, Melanie, Mellal, Nacera, Varela, Aurora, Mann, Peter, Jolette, Jacquelin, Samadfam, Rana, Smith, Susan Y., Locher, Kathrin, Buntich, Sabina, Ominsky, Michael S., Pyrah, Ian, Boyc

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.45 MB

english, 2016

19

Immunohistological study of the cutaneous delayed type hypersensitivity reaction in sheep

Ian T.G. Pyrah, Neil J. Watt

Journal:

Veterinary Immunology and Immunopathology

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

20

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period

Boyce, Rogely W., Varela, Aurore, Chouinard, Luc, Bussiere, Jeanine L., Chellman, Gary J., Ominsky, Michael S., Pyrah, Ian T.

Journal:

Year:

2014

Language:

english

File:

PDF, 7.57 MB

english, 2014

21

Expression of the Immediate–Early Genes, c-fos,c-jun,and c-myc:A Comparison in Rats of Nongenotoxic Hepatocarcinogens with Noncarcinogenic Liver Mitogens

Susan C. Hasmall, Ian T.G. Pyrah, Anthony R. Soames, Ruth A. Roberts

Journal:

Fundamental and Applied Toxicology

Year:

1997

Language:

english

File:

PDF, 703 KB

english, 1997

22

Toxicologic Lesions Associated with Two Related Inhibitors of Oxidosqualene Cyclase in the Dog and Mouse

Pyrah, Ian T., Kalinowski, Adam, Jackson, David, Davies, Wendy, Davis, Stewart, Aldridge, Andrew, Greaves, Peter

Journal:

Toxicologic Pathology

Year:

2001

Language:

english

File:

PDF, 1.71 MB

english, 2001

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